Annexin V and anti-Annexin V antibodies: two interesting aspects in acute myocardial infarction

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Annexin V and anti-Annexin V antibodies: two interesting aspects in acute myocardial infarction

BACKGROUND Myocardial infarction is the combined result of environmental factors and personal predispositions. Prothrombotic factors might play an important role in this phenomenon. Annexin V (ANV) is a calcium-dependent glycoprotein widely present in various tissues exerting a potent anticoagulant effect in vitro by reducing plaque adhesion and aggregation. Anti-annexin V antibodies (aANVAs) a...

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Annexin V expression and anti-annexin V antibodies in type 1 diabetes.

BACKGROUND Annexin V (AnxV) has potent anticoagulant properties and regulatory functions for apoptosis and inflammation. Antibodies against annexin V (anti-AnxVs) may inhibit AnxV functions, leading to thrombosis during autoimmune diseases. Type 1 diabetes is an autoimmune disease and related with an ongoing autoimmune inflammation and thrombotic complications. There is no study evaluating anti...

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[Annexin V levels in survivors of early myocardial infarction].

INTRODUCTION AND OBJECTIVES Annexin V has an anticoagulant effect in vitro that derives from its ability to displace coagulation proteins from phospholipid surfaces, prolonging phospholipid-dependent coagulation reactions. Antiphospholipid antibodies (APL) and annexin V have an affinity for anionic phospholipids, so it has been hypothesized that one of the thrombotic mechanisms of APL may be du...

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Annexin V Levels in Young Patients with Acute Myocardial Infarction: New Answers Bring New Questions

Rev Esp Cardiol 2002;55(12):1223-5 1223 The sharp reduction in coronary blood flow produced by a thrombus generally precipitates acute or unstable coronary syndromes (ACS). Unlike venous thrombosis, arterial thrombosis takes place in areas where the vessel wall is damaged in some way. In the coronary arteries, the lesion usually is a fissured or ruptured atheroma plaque, endothelial denudation ...

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[Annexin V levels in young patients with acute myocardial infarction: new answers bring new questions].

Rev Esp Cardiol 2002;55(12):1223-5 1223 The sharp reduction in coronary blood flow produced by a thrombus generally precipitates acute or unstable coronary syndromes (ACS). Unlike venous thrombosis, arterial thrombosis takes place in areas where the vessel wall is damaged in some way. In the coronary arteries, the lesion usually is a fissured or ruptured atheroma plaque, endothelial denudation ...

متن کامل

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ژورنال

عنوان ژورنال: Thrombosis Journal

سال: 2009

ISSN: 1477-9560

DOI: 10.1186/1477-9560-7-13